Welcome aboard, Pat!
"Nice clothes" are over-rated. :wink: Just funnin'... after 3+ years and lots of miles on our CD-25, we have not come across a place we wanted to visit while cruising that required a jacket and tie.

Travel clothes work well, are less prone to wrinkling, and generally hold up well. You didn't mention if you travel with someone. It's the two of us and a cat on our travels, and we use every available space on our boat. There is storage under the sink, under both foot wells for the helm and co-pilot, under the table. The 25 also has a cabinet across from the enclosed head (see recent posts for different names for that storage locker) and shelves on either side of the v-berth. You can also make storage space with nets or additional shelving... some have added a shelf directly under the table or at the ceiling.
As far as what to take: what would you take with you if you were going on an extended vacation and needed to keep it to two bags? Easy to find space for that on the boat, plus you will need cooking utensils. dishes, and food. You have to decide if you will be using a cooler or install a fridge. Will you need entertainment (stereo, TV, computer, books, iPod, etc, etc). Time of year will dictate the "season" of clothing.
Along the ICW, you will be able to find food, fuel, supplies readily available. You'll want charts and cruising guides.
Comfortable chairs for the cockpit are a must for us. We generally carry a dinghy on top of the boat.
Will you want radar, autopilot, and a chartplotter? We find them invaluable. A Wallas stove/heater keeps the cabin comfortable on those chilly nights.
Pack a sense of humor, leave the tight scheduling at home.
These boats with their shoal draft, comfortable cabins, and ease of handling make great compact cruisers.
Hope that helps get you started. This forum is a great place for info on cruising with these boats.
Best wishes,
Jim B.