Hi Terry,
It wasn't for a CD-22 cover, but I used about 3/4 of a 16 oz bottle to do just the Sunbrella bimini on our 25. The instructions say to do a couple light coats, as opposed to one wet coat.
We did notice that lint stuck to the bimini more than before treatment... it had a somewhat tacky feel to it, even letting the treatment dry between coats.
If it is for an entire boat cover, I would be inclined to say that one 16 oz bottle may not be enough.
Hope that helps,
Jim B.