George nailed it for me, too.
In the past, I lived aboard a "full sized" boat (not that it was so huge, but I mean a 30-footer heavy sail boat, so basically a big sturdy boat with all my stuff aboard).
What do I miss from that? Well, I do miss the big boat feel in the accommodations. By that I don't really mean luxury or space (as it was not that luxurious or large), but more the sturdy/nautical feel of it, plus the fact that I had everything there with me and was aboard all the time. I could go long distance, carry month's worth of provisions, all my tools, etc. I never had to shift from tow vehicle/camper to boat to house to boat to etc.
I don't have that in the 22, but I love it for my current mission, which is trailering to various places and enjoying them in simplicity. Shallow draft, simple, small, light and airy. It fits my mission and I love it for that. I can also stow it away reasonably easily if I want to do something else. So while I do miss some of the things from the first category, they come along with other things that I don't want/need right now.
I guess you could sum it all up in "horses for courses."